PolysacDB Core oligosaccharide 2295
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Core oligosaccharide
[edit] Carbohydrate Class
Core oligosaccharide [LPS]
[edit] Source Microbe
Shigella spp.
[edit] Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The O-antigen consists of the following residues : -3)-β-D-Quip4NAc-(1-->2)-α-D-Manp [branched to α-L-Rhap-(1-->3)] -(1-->4)-β-D-Galp-(1-->3)-α-D-GlcpNAc-(1-
[edit] Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
[edit] Antigenic Nature used to produce antibodies
Heat killed cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 4D64B9
[edit] Antibody type and class
N/A
[edit] Assay System
Indirect ELISA
[edit] Cross-reactivity
This Mab was reactive to S. flexneri and S. boydii
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab has potential importance in immunological detection of Shigella from unknown samples
