PolysacDB Cell surface polysaccharide alginate 2052

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

cell surface polysaccharide alginate

[edit] Carbohydrate Class

Miscellaneous

[edit] Source Microbe

Pseudomonas aeruginosa

[edit] Basic Structure

N/A

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Purified alginate

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab F428

[edit] Antibody type and class

IgG1

[edit] Assay System

ELISA and protection assays

[edit] Cross-reactivity

N/A

[edit] Proposed epitopes

intact carboxylate groups on the C6 carbon of the mannuronic acid residues

[edit] Proposed Utility

This Mab was found to promote phagocytic killing of both mucoid and nonmucoid strains as well as conferred protection against both types of strains in a mouse model of acute pneumonia

[edit] Weblink

PubMed

[edit] External Links

• Link to PolysacDB database