PolysacDB Capsular polysaccharide 1522
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Capsular polysaccharide
[edit] Carbohydrate Class
Capsular polysaccharide
[edit] Source Microbe
Klebsiella pneumoniae
[edit] Basic Structure
N/A
[edit] Proposed functions
CPS have been shown to be important virulence factors and potent Ag for the induction of immunoprotection
[edit] Antigenic Nature used to produce antibodies
A 24-valent K. pneumoniae CPS vaccine containing the serotypes 2, 3, 5, 9, 10, 15, 16. 17, 18, 21, 22, 25, 28. 30, 35, 43, 52, 53, 55, 60, 61, 62, 63, and 64
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab MT72 H99
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA and immunofluorescence
[edit] Cross-reactivity
This Mab recognised K5, K6, K7, K10, K20, K49, K61, K62, K64 and K74 strains
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab may prove valuable as diagnostic tools and that an immunotherapy is feasible