PolysacDB Capsular polysaccharide 1020
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Capsular polysaccharide
[edit] Carbohydrate Class
Capsular polysaccharide
[edit] Source Microbe
Cryptococcus neoformans
[edit] Basic Structure
The capsular polysaccharide has a linear α-(1-->3)-linked mannose backbone that is substituted with nonreducing D-xylosyl and D-glucuronosyl acid groups. The mannose backbone is partially O-acetylated
[edit] Proposed functions
The capsular polysaccharide is an important virulence factor
[edit] Antigenic Nature used to produce antibodies
Cryptococci cells
[edit] Carrier Name
N/A
[edit] Conjugation Method
N/A
[edit] Antibodies
Mab 12G5
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA
[edit] Cross-reactivity
This antibody was specific to D serotype and cross-reacted with GH strain
[edit] Proposed epitopes
N\A
[edit] Proposed Utility
This antibody was shown to bind to cryptococcal capsule
