Pasteurella haemolytica
From DrugPedia: A Wikipedia for Drug discovery
Pasteurella haemolytica
It is a species of gram-negative, facultatively anaerobic, rod-shaped bacteria normally found in the flora of cattle and sheep.
| Kingdom | Bacteria |
|---|---|
| Phylum | Proteobacteria |
| Class | Gamma Proteobacteria |
| Order | Pasteurellales |
| Family | Pasteurellaceae |
| Genus | Pasteurella |
| Species | P. haemolytica |
| Binomial | Pasteurella haemolytica |
[edit] Surface Characteristics
The cell surface lipopolysaccharide (LPS) of Pasteurella haemolytica serotype 1 is composed of three regions consisting of lipid A, core oligosaccharides, and O-antigen polysaccharides. The O-antigen part consists of the following residues : -3)-β-D-Galp-(1-->3)-β-D-GalpNAc-(1-->4)-β-D-Galp-(1-. The core oligosaccharide part consists of the following residues : β-D-Galp-(1-->7)-D-gro-α-D-manHepp-(1-->6)-D-gro-α-D-manHepp-(1-->6)-β-D-Glcp-(1-->4)-L-gro [branched to L-gro-α-D-manHepp-(1-->2)-L-gro-α-D-manHepp-(1-->3)] and [branched to α-D-Glcp-(1-->6)] -α-D-manHepp-(1--/lipid A
[edit] Pathogenic Activity
It causes mastitis in sheep and shipping fever (see pasteurellosis, pneumonic) in cattle.
