Nuclear receptor subfamily 3 group C member 3
From DrugPedia: A Wikipedia for Drug discovery
Contents |
[edit] Source Organism
Canis familiaris (Dog).
[edit] Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.
[edit] Subcellular Localization
Nucleus. Note=Diverse nuclear localization patterns of PR observed in tumorous mammary and uterine tissue, including strong nuclear or perinuclear localization, heterogeneous expression or complete lack of expression, depending on tumor type and stage.
[edit] Developmental Stage
[edit] Similarity
Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
[edit] Post translational Modification
[edit] Function
The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.