Nuclear receptor subfamily 3 group B member 3;
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Contents |
[edit] Source Organism
Homo sapiens (Human).
[edit] Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.
[edit] Subcellular Localization
Nucleus (Probable).
[edit] Developmental Stage
Expressed at high levels in fetal brain and also in the fetal kidney, lung and liver.
[edit] Similarity
Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
[edit] Post translational Modification
[edit] Function
Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).