Nuclear receptor subfamily 3 group B member 3;

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Contents

[edit] Source Organism

Homo sapiens (Human).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;Catarrhini; Hominidae; Homo.

[edit] Subcellular Localization

Nucleus (Probable).

[edit] Developmental Stage

Expressed at high levels in fetal brain and also in the fetal kidney, lung and liver.

[edit] Similarity

Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.

[edit] Post translational Modification

[edit] Function

Orphan receptor that acts as transcription activator in the absence of bound ligand. Binds specifically to an estrogen response element and activates reporter genes controlled by estrogen response elements (By similarity).