Nuclear receptor subfamily 3 group B member 1;

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Contents

[edit] Source Organism

Canis familiaris (Dog).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Canidae;Canis.

[edit] Subcellular Localization

Nucleus (By similarity).

[edit] Developmental Stage

[edit] Similarity

Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.

[edit] Post translational Modification

Phosphorylated (Probable).

[edit] Function

Binds to an ERR-alpha response element (ERRE) containing a single consensus half-site, 5'-TNAAGGTCA-3'. Can bind to the medium-chain acyl coenzyme A dehydrogenase (MCAD) response element NRRE-1 and may act as an important regulator of MCAD promoter. May function as a modulator of the estrogen signaling pathway in the uterus (By similarity).