Nuclear receptor subfamily 3 group A member 2-B;
From DrugPedia: A Wikipedia for Drug discovery
Contents |
[edit] Source Organism
Carassius auratus (Goldfish).
[edit] Taxomomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;Cyprinidae; Carassius.
[edit] Subcellular Localization
Nucleus.
[edit] Developmental Stage
[edit] Similarity
Belongs to the nuclear hormone receptor family. NR3 subfamily. Contains 1 nuclear receptor DNA-binding domain.
[edit] Post translational Modification
[edit] Function
Binds estrogens with an affinity similar to that of ER- alpha, and activates expression of reporter genes containing estrogen response elements (ERE) in an estrogen-dependent manner.