Nuclear receptor subfamily 1 group B member 2

From DrugPedia: A Wikipedia for Drug discovery

Jump to: navigation, search

Contents

[edit] Source Organism

Gallus gallus (Chicken).

[edit] Taxomomy

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;Neognathae; Galliformes; Phasianidae; Phasianinae; Gallus.

[edit] Subcellular Localization

Nucleus.

[edit] Developmental Stage

[edit] Similarity

Belongs to the nuclear hormone receptor family. NR1 subfamily. Contains 1 nuclear receptor DNA-binding domain.

[edit] Post translational Modification

[edit] Function

This is a receptor for retinoic acid. This metabolite has profound effects on vertebrate development. Retinoic acid is a morphogen and is a powerful teratogen. This receptor controls cell function by directly regulating gene expression.