Nuclear receptor subfamily 0 group A member 1;

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Contents

[edit] Source Organism

Drosophila melanogaster (Fruit fly).

[edit] Taxomomy

Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha;Ephydroidea; Drosophilidae; Drosophila; Sophophora.

[edit] Subcellular Localization

Nucleus.

[edit] Developmental Stage

[edit] Similarity

Belongs to the nuclear hormone receptor family. NR0 subfamily. Contains 1 nuclear receptor DNA-binding domain.

[edit] Post translational Modification

[edit] Function

Transcriptional repressor. Binds to multiple sites in the eve stripe 3 enhancer element. Plays an essential role in the segmentation process both by refining the expression patterns of gap genes and by establishing pair-rules stripes of gene expression.