Nuciferine

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Nuciferine
Systematic (IUPAC) name
N/A
Identifiers
CAS number	?
ATC code	?
PubChem	10146
Chemical data
Formula	C19H21NO2
Mol. mass	295.37554
SMILES	eMolecules & PubChem
Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?

[edit] Description

CNS depressant; glutamic acid antagonist; RN given refers to (R)-isomer; structure

Nuciferine is an alkaloid found within the plants Nymphaea caerulea and Nelumbo nucifera. It has a profile of action associated with dopamine receptor blockade. It induces catalepsy, it inhibits spontaneous motor activity, conditioned avoidance response, amphetamine toxicity and stereotypy.

[edit] General Properties

*Molecular Weight

295.37554

*Molecular Formula

C₁₉H₂₁NO₂

*IUPAC NAME

N/A

*Canonical Smiles

CN1CCC2=CC(=C(C3=C2C1CC4=CC=CC=C43)OC)OC

*Isomeric Smiles

CN1CCC2=CC(=C(C3=C2[C@H]1CC4=CC=CC=C43)OC)OC

*XLogP

3.1

*Topological Polar Surface Area

21.7

[edit] External Links

• Pubchem

Link to BIAdb Database