List of Mtu strains available in UniProt
From DrugPedia: A Wikipedia for Drug discovery
This list is manually generated. There is no way to get all of the HAMAP links through a single search.
- note that there is a single number to search for any Mtu complex protein, so use "taxonomy:77643" for that
- 'plain Mtu' (Sanger genome) (complete in v.24 2009-Dec-15, 40% reviewed): MYCTU (ambigous) sequences, taxonomy #1773
- according to the taxonomy page, the Sanger genome includes the strains ATCC 25618 / H37Rv, ATCC 35801 / TMC 107 / Erdman, Erdmann, An03, CDC 1551 / Oshkosh, Canetti, Isolate 50410, and Mt103
- this is the parent taxonomy number, so searching for it using "organism:1773" will give you the Sanger proteome but you can expand the search to all Mtu (except bovis) sequences by using "taxonomy:1773"
- note, however, that both CDC 1551 and Erdman have also separate taxonomy numbers!
- strain KZN 1435/MDR (complete in v.24 2009-Dec-15): MYCTK sequences (all unreviewed), taxonomy #478434
- strain ATCC 25177 / H37Ra (complete in v.24 2009-Dec-15, 10% reviewed): MYCTA sequences, taxonomy #419947
- strain F11 (complete, unreviewed): MYCTF sequences, taxonomy #336982
- strain Haarlem: (not marked complete, 3600 sequences) MYCTU (ambigous) sequences, taxonomy #395095
- strain C (not marked complete, 3500 sequences): MYCTU (ambigous) sequences, taxonomy #348776
- M. bovis strain ATCC BAA-935 / AF2122/97 (Sanger genome) (complete in v.24, 30% reviewed): MYCBO (ambigous) sequences, taxonomy #1765
- according to the taxonomy page, the Sanger genome includes ten strains which also have their own taxonomy numbers
- this is the parent taxonomy number for M. bovis, so searching for it using "organism:1765" will give you the Sanger proteome but you can search for all all Mtu bovis sequences with "taxonomy:1765"
- M. bovis strain BCG / Pasteur 1173P2 (complete in v.24, only 10% reviewed): MYCBP sequences, taxonomy #410289
- M. bovis strain BCG / Tokyo 172 / ATCC 35737 / TMC 1019 (complete in v.24, less than 10% reviewed): MYCBT sequences, taxonomy #561275
Are there other strains of Mtu in UniProt we should be aware of?
Minor addition: there are also less than 100 sequences of strain H37Rv and of subsp. tuberculosis.