Diuretic hormone class 1

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 Source Organism 3 Taxomomy 4 Subcellular Localization 5 Developmental Stage 6 Similarity 7 Post translational Modification 8 Function 9 GeneID

[edit] Description

Diuretic hormone class 1 (Diuretic hormone class I) (Diuretic peptide)(DP) (DH(46)).

[edit] Source Organism

Diploptera punctata (Pacific beetle cockroach).

[edit] Taxomomy

Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Orthopteroidea; Dictyoptera; Blattaria; Blaberidae;Diplopterinae; Diploptera.

[edit] Subcellular Localization

Secreted protein.

[edit] Developmental Stage

[edit] Similarity

Belongs to the sauvagine/corticotropin-releasing factor/urotensin I family.

[edit] Post translational Modification

[edit] Function

Regulation of fluid secretion. Stimulates primary urine secretion by Malpighian tubules and causes a dose-dependent stimulation of cAMP levels in the tubules. Has a greater effect on the transport of Na(+) then K(+) ions. In vitro, has synergistic effects with the smaller diuretic hormone DH(31) which co-occurs with it

[edit] GeneID