CarboDB Unknown carbohydrate 1542
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Unknown carbohydrate
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Leishmania tropica (LRC-L137)
[edit] Basic Structure
N/A
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
L. tropica (LRC-L137) promastigotes
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab L-5-85
[edit] Antibody type and class
IgG2a
[edit] Assay System
solid-phase radioimmunoassay, Indirect fluorescent antibody test
[edit] Cross-reactivity
This Mab cross-reacted with 4 strains of L. tropica - L137, L287, L251, L38. It also cross-reacted with L. enriettii L144 strain
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab would allow the study of the origin and the location of the Leishmania spp. antigens on the macrophage membrane as well as the characterization of these antigens in terms of their relationship to host histocompatibility antigens involved in antigen presentation