CarboDB Streptococcal A carbohydrate 2420
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Streptococcal A carbohydrate
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Streptococci Group A
[edit] Basic Structure
N/A
[edit] Proposed functions
This Carbohydrate is highly immunodominant
[edit] Antigenic Nature used to produce antibodies
Sera of humans having IgM myeloma
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab AC179
[edit] Antibody type and class
IgM
[edit] Assay System
solid-phase enzyme-linked immunoassay, Streptococcal agglutination assay
[edit] Cross-reactivity
ACI79 was most active in agglutinating A variant (Av) and group C streptococci
[edit] Proposed epitopes
AC179 is directed to α-linked rhamnose oligosaccharides
[edit] Proposed Utility
AC179 induced complement activation in the presence of the carbohydrate
