CarboDB O-polysaccharide 2065
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Pseudomonas syringae serogroup O1 strain atrofaciens NCPPB 2612
[edit] Basic Structure
O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab Ps1C1
[edit] Antibody type and class
IgG3
[edit] Assay System
ELISA, agglutination and immunoblotting
[edit] Cross-reactivity
This Mab showed strong reactivity with OPS of chemotype 1C and weak reactivity with OPS of chemotype 1C-1A with a low content of 1A linear O repeats
[edit] Proposed epitopes
The epitope is related to the lateral D-GlcNAc residue and also one or more D-Rha residues of the backbone 1A and is more influenced by the protein-dependent conformation of the OPS chain
[edit] Proposed Utility
This Mab agglutinated heat-killed homologous bacterial cells
