CarboDB O-polysaccharide 1504
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Actinobacillus pleuropneumoniae serotype b strain 81-750
[edit] Basic Structure
It consists of linear unbranched polysaccharide structure
[edit] Proposed functions
LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
[edit] Antigenic Nature used to produce antibodies
formaldehyde killed cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 1A3
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA and dot ELISA
[edit] Cross-reactivity
This antibody cross-reacted strongly with strain L20 CPS (serotype 5b)
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals
