CarboDB O-polysaccharide 1503
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Acinetobacter baumannii strain 24
[edit] Basic Structure
Acinetobacter LPSs consist of a polysaccharide covalently linked to a lipid component, termed lipid A, which anchors the LPS in the outer membrane. This polysaccharide is divided into the core oligosaccharide (linked to lipid A) and the O-polysaccharide or O-antigen. This type of LPS is referred to as the smooth- or S-form phenotype; the O-antigens are characteristic for a given LPS and the parental bacterial strain
[edit] Proposed functions
Since all recently investigated LPSs from Acinetobacter strains have been shown to be of the smooth phenotype, a serotyping scheme for identification of members of this genus may also be possible
[edit] Antigenic Nature used to produce antibodies
Heat killed bacteria
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Polysera
[edit] Antibody type and class
N/A
[edit] Assay System
Enzyme immunoassay
[edit] Cross-reactivity
The antisera cross-reacted with 13 strains A. baumannii
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals
