CarboDB O-polysaccharide 1501

From DrugPedia: A Wikipedia for Drug discovery

Jump to: navigation, search


Contents

[edit] Carbohydrate Name

O-polysaccharide

[edit] Carbohydrate Class

O-polysaccharide [LPS]

[edit] Source Microbe

Acinetobacter baumannii strain 24

[edit] Basic Structure

Acinetobacter LPSs consist of a polysaccharide covalently linked to a lipid component, termed lipid A, which anchors the LPS in the outer membrane. This polysaccharide is divided into the core oligosaccharide (linked to lipid A) and the O-polysaccharide or O-antigen. This type of LPS is referred to as the smooth- or S-form phenotype; the O-antigens are characteristic for a given LPS and the parental bacterial strain


[edit] Proposed functions

Since all recently investigated LPSs from Acinetobacter strains have been shown to be of the smooth phenotype, a serotyping scheme for identification of members of this genus may also be possible

[edit] Antigenic Nature used to produce antibodies

Heat killed bacteria

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab S48-3-13

[edit] Antibody type and class

IgG3

[edit] Assay System

Dot blot and Enzyme Immunoassay

[edit] Cross-reactivity

This antibody cross-reacted with 31 strains A. baumannii

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This antibody can be used for strain identification in A. baumanni species

[edit] Weblink

PubMed Central

[edit] External Links