CarboDB O-polysaccharide 1242
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Brucella abortus W99
[edit] Basic Structure
O-polysaccharide consists of an unbranched linear homopolymer of 10 to 100 α-1,2-linked 4-formamido-4,6-dideoxy-D-mannose (N formylperosamine) residues. The O-polysaccharide is covalently linked to a core oligosaccharide
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Whole B. abortus W99 cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 2C8C4
[edit] Antibody type and class
IgG3
[edit] Assay System
ELISA
[edit] Cross-reactivity
This Mab was specific to A strains of Brucella and did not cross-react with Brucella M strain, Y enterocolitica O:9, S-LPSs of S.urbana, Vibrio cholerae and E. coli O:157
[edit] Proposed epitopes
The epitope was proposed to be a pentasaccharide or larger oligosaccharide composed of α1,2-linked D-Rha4NFo and also contained α1,3 linkages
[edit] Proposed Utility
This Mab helped in the epitope strucure elucidation
