CarboDB O-polysaccharide 1111
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Actinobacillus pleuropneumoniae serotype 5 strain 91-178-2005
[edit] Basic Structure
O chains of LPS of are composed of repeating tetrasaccharide units with identical trisaccharide residues forming a common backbone
[edit] Proposed functions
LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
[edit] Antigenic Nature used to produce antibodies
formalinized whole cell antigen (WCA)
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 6.1E7.E3
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA, immunoblotting
[edit] Cross-reactivity
This antibody specifically reacted with Serotype5 only
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This MAb could be useful for serotyping analysis in actinobacillus strains
