CarboDB Lipopolysaccharide and capsular polysaccharide 1511

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Contents

[edit] Carbohydrate Name

Lipopolysaccharide and capsular polysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Actinobacillus pleuropneumoniae serotype b strains 81-750 and B78-3760

[edit] Basic Structure

Consists of a polysaccharide structure of a linear unbranched


[edit] Proposed functions

LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus

[edit] Antigenic Nature used to produce antibodies

formaldehyde killed cells of strains 81-750 and B78-3760 and LPS coated whole cells of strain 81-750.

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 3A5

[edit] Antibody type and class

IgG1

[edit] Assay System

ELISA and dot ELISA

[edit] Cross-reactivity

This antibody cross-reacted strongly with CPS of serotype 5b

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals

[edit] Weblink

PubMed Central

[edit] External Links