CarboDB Lipopolysaccharide 2072
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Pseudomonas aeruginosa strain Fisher IT-4
[edit] Basic Structure
The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The core oligosaccharide of P. aeruginosa can be divided into outer and inner core regions. The inner core consists of 2-keto-3-deoxyoctonate (Kdo), heptose, and large amounts of phosphate and is believed to be homogeneous among serotypes. The outer core of P. aeruginosa contains D-glucose (D-Glc), L-rhamnose (L-Rha), D-galactosamine (D-GalN), and L-alanine (L-Ala]
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
alkali treated LPS
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Antisera
[edit] Antibody type and class
N/A
[edit] Assay System
ELISA, opsonophagocytic assays, animal protection studies and immunoblotting
[edit] Cross-reactivity
This antisera was specific to strain IT-4
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This antisera had opsonophagocytic activity against LPS rough strains
