CarboDB Lipopolysaccharide 1561
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Leptospira interrogans serovar copenhageni
[edit] Basic Structure
N/A
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
a suspension of serovar copenhageni strain H45 leptospires
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab MUM/F 1 - 1 /copenhageni
[edit] Antibody type and class
IgA
[edit] Assay System
enzyme immunoassay, immunodiffusion and immunoblotting, Passive protection experiments
[edit] Cross-reactivity
This Mab reacted with 1 1 of the 17 serovars of the Icterohaemorrhagiae serogroup, but did not react significantly with representative serovars of the other serogroups of L. interrogans or other species of Leptospira
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab opsonised viable leptospires for phagocytosis and was further shown to protect against lethal infection in susceptible animals