CarboDB Lipopolysaccharide 1513
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Klebsiella strains KD2
[edit] Basic Structure
O-1 side chain of the LPS is proposed to contain a disaccharide repeat unit consisting of [-α-D-Galp-(1->3)-β-D-Galf-] (1->4), where Gal is galactose
[edit] Proposed functions
These major cell surface antigens play important roles in the ability of the bacterium to evade host cell defenses
[edit] Antigenic Nature used to produce antibodies
formalinized whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Polysera
[edit] Antibody type and class
N/A
[edit] Assay System
ELISA and immunoblotting
[edit] Cross-reactivity
The antisera reacted most strongly against the HMW-LPS fraction of Kliebsiella strain KD2 but also recognized the LMW-LPS of KLebsiella strains KD37 and KD2
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This antibody may help in the stuctural and functional elucidation of O1 side chain of Klebsiella LPS
