CarboDB Lipopolysaccharide 1510

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Actinobacillus pleuropneumoniae serotype b strains 81-750 and B78-3760

[edit] Basic Structure

Consists of a polysaccharide structure of a linear unbranched

[edit] Proposed functions

LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus

[edit] Antigenic Nature used to produce antibodies

formaldehyde killed cells of strains 81-750 and B78-3760 and LPS coated whole cells of strain 81-750.

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 3B4

[edit] Antibody type and class

IgG1

[edit] Assay System

ELISA and dot ELISA

[edit] Cross-reactivity

This antibody cross-reacted strongly with CPS of serotype 5b

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab can be used to detect the presence of bacterial antigens in lungs from infected animals

[edit] Weblink

PubMed Central

[edit] External Links

• Link to CarboDB database