CarboDB Lipopolysaccharide 1365
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Chlamydia pneumoniae TW-183
[edit] Basic Structure
It has the core lipid A moiety and 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) core but lacks the distal O-polysaccharide region
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab CP-33
[edit] Antibody type and class
IgG2b
[edit] Assay System
N/A
[edit] Cross-reactivity
This Mab recognized the LPSs of C. pneumoniae, Chlamydia trachomatis, and Chlamydia psittaci but did not react with 15 genera of gram-negative and gram-positive bacteria and Candida albicans
[edit] Proposed epitopes
This Mab recognizes a trisaccharide epitope αKdo(2-->8) αKdo(2-->4)αKdo
[edit] Proposed Utility
This Mab neutralizes both in vitro and in vivo the infectivity of C. pneumoniae
