CarboDB Lipopolysaccharide 1189
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Yersinia enterocolitica 0:9
[edit] Basic Structure
The O-antigen part consists of the following residues : -2)-α-D-Rhap4NFo-(1-
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Killed whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Ys.T9-5
[edit] Antibody type and class
IgG1
[edit] Assay System
Whole cell agglutination, immunodiffusion, immunoblotting and ELISA
[edit] Cross-reactivity
This Mab was specific to Y. enterocolitica and did not cross-react with Brucella abortus LPS
[edit] Proposed epitopes
The epitope was proposed to be partially directed to the core that gave rise to its specificity to Y. enterocolitica. The study also indicates that the portion of the O-antigen recognized is most probably an oligosaccharide portion which encompasses elements of both the O-chain and the core
[edit] Proposed Utility
This Mab can be used to study the cell wall polysaccharide antigens of other Y. enterocolitica strains and are being evaluated for specific serological identification of B. abortus.
