CarboDB Lipopolysaccharide 1092
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Actinobacillus pleuropneumoniae
[edit] Basic Structure
O chains of LPS of serotypes 4 and 7 were structurally similar, being composed of repeating tetrasaccharide units with identical trisaccharide residues forming a common backbone
[edit] Proposed functions
LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
[edit] Antigenic Nature used to produce antibodies
whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
2Mab5
[edit] Antibody type and class
IgG2a
[edit] Assay System
Elisa inhibition assay
[edit] Cross-reactivity
N/A
[edit] Proposed epitopes
O-antigenic polysaccharide moeity inside the LPS. The epitope was proposed to include O-acetyl group of C6 position of glucose in the middle of repeating units
[edit] Proposed Utility
N/A
