CarboDB Lipopolysaccharide 1089
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Eikenella corrodens FDC 1073
[edit] Basic Structure
The LPS of E. corrodens was found to have little 2-keto-3-deoxyocutulosonic acid (KDO) and heptose and fairly strong classical endotoxic activities
[edit] Proposed functions
The lipopolysaccharide (LPS) of the species may play a primary role in the pathogenesis
[edit] Antigenic Nature used to produce antibodies
LPS preparations from E. corrodens FDC
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab ECF-3
[edit] Antibody type and class
IgG3
[edit] Assay System
ELISA, immunodiffusion, immunoblotting
[edit] Cross-reactivity
This antibody cross-reacted with LPSs from C. ochracea M-12 and F. necrophorum ATCC 25286
[edit] Proposed epitopes
The epitope consists of D-galactose and L-rhamnose residues and recognizes an O-side chain epitope
[edit] Proposed Utility
This Mab would help in the revealing of antigenic natureof the surface of Eikenella corrodens
[edit] Weblink
[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC313151 &tool=pmcentrez&rendertype=abstract PubMed Central]
