CarboDB Lipopolysaccharide 1057

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Escherichia coli O26:H11

[edit] Basic Structure

The O-polysaccharide is composed of trisaccharide repeating units having the following structure. -->3)-α-L-Rhap-(1-->4)-α-L-FucpNAc-(1-->3)-β-D-GlcpNAc-(1-->

[edit] Proposed functions

N/A

[edit] Antigenic Nature used to produce antibodies

Whole cells

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab 12F5

[edit] Antibody type and class

IgM

[edit] Assay System

ELISA, immunoblotting

[edit] Cross-reactivity

This antibody cross-reacted with E. coli O4:NM strain and other E. coli O-negative:NM field isolates

[edit] Proposed epitopes

O-antigen was proposed to be the epitope

[edit] Proposed Utility

These MAb have a potential use as immunodiagnostic reagents whether used alone or in combination with other phenotypic or genotypic markers

[edit] Weblink

[http://www.pubmedcentral.nih.gov/articlerender.fcgi?artid=PMC92269 &tool=pmcentrez&rendertype=abstract PubMed Central]

[edit] External Links

• BCSDB Structural Detail

• Link to CarboDB database