CarboDB Lipooligosaccharide 1619
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipooligosaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Moraxella catarrhalis serotype C
[edit] Basic Structure
LOS consists of an oligosaccharide and lipid A and is similar to the lipopolysaccharide (LPS) of gramnegative enteric pathogens, but it lacks the O-antigenic side chain of repeating units characteristic of classical LPS. The oligosaccharide part consists of the following residues : α-D-Galp-(1-->4)-β-D-Galp-(1-->4)-α-D-Glcp-(1-->2)-β-D-Glcp-(1-->6)-α-D-Glcp [branched to β-D-Galp-(1-->4)-α-D-GlcpNAc-(1-->2)-β-D-Glcp-(1-->4)] and [branched to β-D-Glcp-(1-->3)] -(1-->5)-α-Kdop [branched to Kdop-(2-->4)]
[edit] Proposed functions
Moracella lipooligosaccharide is a potential virulence factor
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Polysera
[edit] Antibody type and class
N/A
[edit] Assay System
ELISA and immunoblotting
[edit] Cross-reactivity
This antisera cross-reacted with Serotype A LPS
[edit] Proposed epitopes
A terminal β-D-Gal-(1-->4)-α-D-GlcNA seemed to be a part of the epitope
[edit] Proposed Utility
This antisera may help in sertotyping of moraxella strains
