CarboDB Lipoarabinomannan 1658
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipoarabinomannan
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Mycobacterium leprae
[edit] Basic Structure
Lipoarabinomannan is a complex carbohydrate containing arabinose, mannose, glycerol, and myo-inositol 1-phosphate, in addition to lactate, succinate, palmitate, and 10 methyloctadecanoate
[edit] Proposed functions
T cell proliferation and to interfere with gamma interferon-mediated activation of macrophages
[edit] Antigenic Nature used to produce antibodies
a combination of M. leprae 30KS and 1OKP
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab C94
[edit] Antibody type and class
IgG1
[edit] Assay System
ELISA, immunoblotting
[edit] Cross-reactivity
This Mab was specific for M. leprae LAM
[edit] Proposed epitopes
α(1-->5)-linked arabinofuranosyl residues seemed to be a part of the epitope
[edit] Proposed Utility
This Mab would help in the structure elucidation of lipoarabinomanna
