CarboDB Exopolysaccharide 1253
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Exopolysaccharide
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Burkholderia pseudomallei NCTC 4845
[edit] Basic Structure
N/A
[edit] Proposed functions
Polysaccharide capsule of B. pseudomallei plays a role in environmental protection, immune system evasion and attachment to epithelial cells
[edit] Antigenic Nature used to produce antibodies
Heat inactivated B. pseudomallei NCTC 4847
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 4VA5
[edit] Antibody type and class
IgG1
[edit] Assay System
ELISA and immunoblotting
[edit] Cross-reactivity
N/A
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This MAb demonstrated a significant protective effect against a challenge dose of B. Pseudomallei in mice