CarboDB Capsular polysaccharide 1522

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Capsular polysaccharide

[edit] Carbohydrate Class

Capsular polysaccharide

[edit] Source Microbe

Klebsiella pneumoniae

[edit] Basic Structure

N/A

[edit] Proposed functions

CPS have been shown to be important virulence factors and potent Ag for the induction of immunoprotection

[edit] Antigenic Nature used to produce antibodies

A 24-valent K. pneumoniae CPS vaccine containing the serotypes 2, 3, 5, 9, 10, 15, 16. 17, 18, 21, 22, 25, 28. 30, 35, 43, 52, 53, 55, 60, 61, 62, 63, and 64

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Mab MT72 H99

[edit] Antibody type and class

IgM

[edit] Assay System

ELISA and immunofluorescence

[edit] Cross-reactivity

This Mab recognised K5, K6, K7, K10, K20, K49, K61, K62, K64 and K74 strains

[edit] Proposed epitopes

N/A

[edit] Proposed Utility

This Mab may prove valuable as diagnostic tools and that an immunotherapy is feasible

[edit] Weblink

PubMed

[edit] External Links

• Link to CarboDB database