Bioinformatics Databases
From DrugPedia: A Wikipedia for Drug discovery
Bioinformatics and computational biology (sometimes called systems biology) involve the use or development of techniques, including applied mathematics, informatics, statistics, computer science, artificial intelligence, chemistry, and biochemistry to solve biological problems, usually on the molecular level. The primary goal of bioinformatics is to increase our understanding of biological processes. What sets it apart from other approaches, however, is its focus on developing and applying computationally intensive techniques (e.g., data mining, and machine learning algorithms) to achieve this goal. Major research efforts in the field include sequence alignment, gene finding, genome assembly, protein structure alignment, protein structure prediction, prediction of gene expression and protein-protein interactions, and the modeling of evolution.
bioinformatics more properly refers to the creation and advancement of algorithms, computational and statistical techniques, and theory to solve formal and practical problems arising from the management and analysis of biological data.Put more simply, bioinformatics is concerned with the information while computational biology is concerned with the hypotheses.
There are a number of Databases that are developed By Bioinformatics Centre(BIC), Institute of Microbiology(Imtech ) Chandigarh, India.
Some of them are as follows :
Contents |
[edit] MHCBN
The MHCBN is a curated database consisting of detailed information about Major Histocompatibility Complex (MHC) Binding,Non-binding peptides and T-cell epitopes.The version 4.0 of database provides information about peptides interacting with TAP and MHC linked autoimmune diseases. This database is Developed by Dr Raghava's Group, at Bioinformatics Centre, Institute of Microbial Technology, Chandigarh, INDIA.
[edit] BCIPEP
The BciPep is a database of B-cell epitops.
The prime/boost vaccine strategy has suggested that only immunodominant epitopes, rather than a large collection of defined epitopes with varying immunogenicity should be selected for vaccines.
[edit] HaptenDB Database
Haptendb is a database of haptens which provide comprehensive information about the Hapten molecule, ways to raise antibodies against particular group of haptens, specificity and cross reactivity of raised antibody with related haptens, use of antibodies in constructing cost effective and simple detection kits. Following are major features
- It covers wide array of haptens that includes; pesticides, herbicides, insecticides, drugs, vitamins, steroids, hormones, toxins, dyes, explosives, etc.
- The database contains 2021 entries for antibodies either raised against haptens or cross-reactivity of antibody raised against one Hapten with other related haptens. Every single record in the database contains detailed information about the Hapten, the carrier and the antibodies along with the assay methods and their sensitivity towards Hapten detection.
- The database provides information about 1087 haptens that includes: (i) common and chemical name of Hapten, (ii) molecular mass, physical and chemical properties, (iii) biological importance and the structure.
- Haptendb provides online web tools that allows users to retrieve and analyze the data that includes: (i) tools for searching database using keywords with many options and, (ii) browsing tool that allows the user to browse the database on Hapten name, carrier protein and antibody.
- The database has 2-D and 3-D structures of most of haptens in standard format based on information in literature. It also allows sketching structures online and searching of similar structures in database
- One of the powerful tools in Haptendb is structure similarity search tool, which allows user to search similar structures.
[edit] PDSB (Public Software in Biology)
PDSB databases consists the computer software in biology. These computer software developed by people for people and are available free to potential users. The software collected on this site will be available on-line free for users via internet (e.g. FTP, Email Server, web browser ). These software would also be available of-line on request on floppy, CD-ROM, DAT Tapes etc., For this off-line service we will charge nominal fee (Postage + handling charges + Media cost) In order to assist the user in finding a desired software availabe, a search engine has been developed which will allow to search a software by its name, keyword, function etc. All software packages are classify in categories based on their function.
[edit] PDWSB(Public Domain Web Servers in Biology)
PDWSBdatabase consists the information about web servers in biology. These web servers developed by people for people for solving the biological problems on line via Internet. These web severs are available free for potentila users.
[edit] PDWPB(Public Domain Web Pages in Biology)
PDWPBdatabase consists the information about web pages in biology. These web pages developed by people for people for providing biological information on line via Internet. These web severs are available free for potential users.
