Antidiuretic factor A

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 Source Organism 3 Taxomomy 4 Subcellular Localization 5 Developmental Stage 6 Similarity 7 Post translational Modification 8 Function 9 GeneID

[edit] Description

Antidiuretic factor A (ADFa) (ADF) (Antidiuretic hormone A) (ADHA).

[edit] Source Organism

Tenebrio molitor (Yellow mealworm).

[edit] Taxomomy

Eukaryota; Metazoa; Arthropoda; Hexapoda; Insecta; Pterygota;Neoptera; Endopterygota; Coleoptera; Polyphaga; Cucujiformia;Tenebrionidae; Tenebrio.

[edit] Subcellular Localization

Secreted.

[edit] Developmental Stage

[edit] Similarity

To T.molitor cuticular protein LPCP29 C-terminal region.

[edit] Post translational Modification

[edit] Function

Strong inhibitor of fluid secretion by the Malpighian tubules. Uses cGMP as a second messenger and inhibits fluid production by decreasing cAMP concentration. Reduces isosmotic fluid secretion by inhibiting electroneutral and non-conductive transport pathways. Reverses the stimulatory effect of diuretic hormone I

[edit] GeneID