5a-Dihydrotestosterone sulfate

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Description 2 General Properties 3 PhysioChemical Properties 4 External Links

[edit] Description

Show 3-D Structure

Dihydrotestosterone (DHT) is a steroid similar to testosterone and androstenedione, that belongs to a class called androgens. DHT is a C19 steroid and possesses androgenic activity. Androgen production takes place mainly in the Leydig cells of the testes. Androgens circulate in the blood bound to proteins, especially sex hormone binding globulin (SHBG) and albumin. A trace amount of these steroids circulate in the unbound form in the blood and are referred to as the free fractions. DHT has at least three times the binding affinity for SHBG than testosterone. About 70% of DHT is derived from peripheral conversion of testosterone in males, while most of the DHT is derived from androstenedione in females. (http://www.biosupply.co.uk/doc.php?id=2296)

[edit] General Properties

*Molecular Weight

370.5

*Molecular Formula

C₁₉H₃₀O₅S

*IUPAC NAME

*Canonical Smiles

CC12CCC(=O)CC1CCC1C3CCC(OS(O)(=O)=O)C3(C)CCC21

*Isomeric Smiles

C[C@]12CCC(=O)C[C@@H]1CC[C@H]1[C@@H]3CC[C@H](OS(O)(=O)=O)[C@@]3(C)CC[C@H]21

[edit] PhysioChemical Properties

*Melting Point

*LogP

*Water Solubility

[edit] External Links

• [1]Human Metabolome DataBase