PolysacDB O-polysaccharide 2056
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Pseudomonas syringae IMV 7836 pv. Atrofaciens
[edit] Basic Structure
O-polysaccharides of the LPS consists of tetra- and tri-α-D-rhamnose repeats in the backbone [-3)D-Rha(α1->3)D-Rha(α1-->2)D-Rha(α1->2)D-Rha(α1] and [3)D-Rha(α1-->3)D-Rha(α1-->2)D-Rha(α1-]
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab Ps1a'
[edit] Antibody type and class
IgG3
[edit] Assay System
Agglutination, Ouchterlony immunodiffusion, ELISA, SDS-PAGE, and Western immunoblotting
[edit] Cross-reactivity
"Mab Ps1a' cross-reacted with all strains from subgroups 1b, 1c, and 1x but not with strains from 1d."
[edit] Proposed epitopes
The epitope of Mab1a' is related to the D-Rha(alpha1-3)D-Rha(alpha1-2)D-Rha site of the O-polysaccharide backbone consisting of tetra-D-rhamnose repeats. The residue (alpha1-3)DRha( alpha1-2) is immunodominant for epitope of Mab 1a'
[edit] Proposed Utility
This Mab was useful for elucidation of the LPs structure
