CarboDB Lipopolysaccharide 1533
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Klebsiella pneumoniae strain R20/O1
[edit] Basic Structure
N/A
[edit] Proposed functions
It is an important virulence factor
[edit] Antigenic Nature used to produce antibodies
heat-killed Klebsiella pneumoniae strain R20/O1
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Un-named Mab
[edit] Antibody type and class
N/A
[edit] Assay System
ELISA and immunoblotting
[edit] Cross-reactivity
The antibody was able to bind to LPS of clinical isolates of K. pneumoniae, K. oxytoca, K. terrigena and K. planticola but did not bind to LPS of other Gram-negative genera
[edit] Proposed epitopes
This Mab recognized the LPS core
[edit] Proposed Utility
This antibody bound only to those LPS molecules which did not carry an O-antigen and thus this antibody is different from those already published
