CarboDB Capsular polysaccharide 1973
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Capsular polysaccharide
[edit] Carbohydrate Class
Capsular polysaccharide
[edit] Source Microbe
Streptococcus pneumoniae strain 14
[edit] Basic Structure
The capsular polysaccharide consists of the following residues : -6)-β-D-GlcpNAc [branched to β-D-Galp-(1-->4)] -(1-->3)-β-D-Galp-(1-->4)-β-D-Glcp-(1-
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Glycoconjugates
[edit] Carrier Name
Tetanus toxoid
[edit] Conjugation Method
The oligosaccharide was derivatized with adipic acid dihydrazide and coupled to tetanus toxoid
[edit] Antibodies
Mab 1F6
[edit] Antibody type and class
IgG1
[edit] Assay System
Enzyme Inhibition Assay, colony blotting, Opsonophagocytosis assay
[edit] Cross-reactivity
This Mab was specific tgo strain 14 and did not cross-react with other strains
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
N/A
