PolysacDB O-polysaccharide 2004
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Pseudomonas aeruginosa serotype 1
[edit] Basic Structure
The LPS consists of three regions, namely O-polysaccharide, core oligosaccharide and lipid A. The O-polysaccharide consists of the following residues : -4)-α-D-GalpNAcA3Ac6NH2-(1-->4)-α-D-GalpNFoA6NH2-(1-->3)-α-D-QuipNAc-(1-->2)-α-L-Rhap-(1-
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
antigen extract from Pseudomonas aeruginosa serotype 1 [PVA-1]
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab ES-P-1S-2
[edit] Antibody type and class
IgG2b
[edit] Assay System
ELISA, passive protection tests
[edit] Cross-reactivity
This Mab was specific to PVA-1 antigen
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
This Mab had invivo protective activity
