PolysacDB O-polysaccharide 1136
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
O-polysaccharide
[edit] Carbohydrate Class
O-polysaccharide [LPS]
[edit] Source Microbe
Actinobacillus pleuropneumoniae serotype 5
[edit] Basic Structure
O-chains of LPS are composed of repeating tetrasaccharide units with identical trisaccharide residues forming a common backbone
[edit] Proposed functions
LPS is an important virulence factor. It molecule plays an important role in adherence of the bacterium to porcine respiratory tract cells and mucus
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
5Mab-1
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA inhibition tests
[edit] Cross-reactivity
This Mab was specific to serotype 5 strains
[edit] Proposed epitopes
The epitope was proposed to consist of of β-1,6-linked D-galactose residues
[edit] Proposed Utility
This Mab can be used for specially distinguishing serotype 5 strains
