PolysacDB Lipopolysaccharide 2210
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Salmonella minnesota Re chemotype 595
[edit] Basic Structure
LPS is a complex macromolecule composed of the biologically active lipid A moiety, covalently attached core oligosaccharide, and distally linked polysaccharide O-side chain. The core oligosaccharide part consists of the following residues : α-Kdop-(2-8)-α-Kdop-(2-->4)-Kdo
[edit] Proposed functions
LPS plays an important virulence role based on its antiphagocytic and endotoxic properties
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab E1
[edit] Antibody type and class
IgG3
[edit] Assay System
direct and inhibition enzyme immunoassays
[edit] Cross-reactivity
MAb E1 reacted exclusively with those of Re-chemotype
[edit] Proposed epitopes
It recognized α-Kdo- monosaccharide and disaccharide structures present as non-reducing side chains in various Re-type LPSs and synthetic antigens
[edit] Proposed Utility
This Mab can be used for identification of Salmonella strains having the Re chemotype
