PolysacDB Lipopolysaccharide 1879
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Neisseria meningitidis group A strain 4402
[edit] Basic Structure
It consists of a homopolymer of α(2-->8)-linked sialic acid residues
[edit] Proposed functions
It is an important virulence factor
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab MCA14.2
[edit] Antibody type and class
N/A
[edit] Assay System
coagglutination, enzyme-linked immunosorbent assay and immunoblotting
[edit] Cross-reactivity
This Mab cross-reacted with a group A strain having the L10 serotype and a group B meningococcal strain and Haemophilus influenzae type B, but not with the lipopolysaccharides of several strains of Salmonella typhi, Escherichia coli, Streptococcus pneumoniae, and Neisseria gonorrhoeae
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
N/A
