PolysacDB Lipopolysaccharide 1786
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Lipopolysaccharide
[edit] Carbohydrate Class
Lipopolysaccharide
[edit] Source Microbe
Myxococcus xanthus
[edit] Basic Structure
It consists of Lipid A region covalently linked to the core region
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab 1412
[edit] Antibody type and class
IgM
[edit] Assay System
ELISA, immunoblotting
[edit] Cross-reactivity
This Mab was specific to M. xanthus and did not bind to LPS of any other gram negative bacteria
[edit] Proposed epitopes
O-antigen of the LPS seems to constitute the epitope
[edit] Proposed Utility
This MAb may be a useful probe for detecting specific alterations in the LPS structure which may occur during the development of M. xanthus. This Mab has been used to isolate many LPS biosynthesis mutants
