PolysacDB Lipopolysaccharide 1155

From DrugPedia: A Wikipedia for Drug discovery

Contents 1 Carbohydrate Name 2 Carbohydrate Class 3 Source Microbe 4 Basic Structure 5 Proposed functions 6 Antigenic Nature used to produce antibodies 7 Carrier Name 8 Conjugation Method 9 Antibodies 10 Antibody type and class 11 Assay System 12 Cross-reactivity 13 Proposed epitopes 14 Proposed Utility 15 Weblink 16 External Links

[edit] Carbohydrate Name

Lipopolysaccharide

[edit] Carbohydrate Class

Lipopolysaccharide

[edit] Source Microbe

Bacteroides fragilis NCTC 9343

[edit] Basic Structure

The polysaccharide part of the LPS mainly consists of two fractions : PSI : β-D-Galp(1-->6)β-D-Galp(1-->6)β-D-Galp(1-->6)Residue1-α-D-Glcp [branched to Residue no. 2](1-->2)α-L-Rhap and PSII : β-D-Galp(1-->4)α-D-Glcp [Branched to β-D-Galp(1-->6)](1-->2)α-L-Rhap

[edit] Proposed functions

LPS polysaccharide of B. fragilis may represent a virulence factor

[edit] Antigenic Nature used to produce antibodies

Whole cells of B. fragilis NCTC 9343

[edit] Carrier Name

nil

[edit] Conjugation Method

nil

[edit] Antibodies

Polysera

[edit] Antibody type and class

N/A

[edit] Assay System

ELISA

[edit] Cross-reactivity

This antisera cross-reacted with 13 strains of B. fragilis

[edit] Proposed epitopes

Galactose chains was proposed to be an important part of the epitope

[edit] Proposed Utility

This antisera can be used in serotyping schemes for this particular bacteria

[edit] Weblink

262078&tool=pmcentrez&rendertype=abstract PubMed Central

[edit] External Links

• Link to PolysacDB database