PolysacDB High molecular weight polysaccharide 1146
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
High molecular weight polysaccharide
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Bacteroides fragilis NCTC 9343
[edit] Basic Structure
-3)α-D-FucpNAc4N(1-->4)α-D-GalpNAc [branched to β-D-Galf(1-->3)] (1-->3)β-D-Galp [branched via 6th and 4th positions to RPyr(2-(1-.C73
[edit] Proposed functions
Capsular polysaccharide of B. fragilis may represent a virulence factor
[edit] Antigenic Nature used to produce antibodies
whole cells of a B. fragilis NCTC 9343 enriched for expression of the EDL
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab QUBf8
[edit] Antibody type and class
IgG1
[edit] Assay System
Immunoblotting, immunofluorescence, flow cytometry
[edit] Cross-reactivity
This Mab did not cross-react with B. vulgatus, B. thetawtaomicron, B. ovatus, B. distasonis, B. gingivalis, E. coli or S. aureus. But it reacted with B. fragilis strain BE6
[edit] Proposed epitopes
N/A
[edit] Proposed Utility
N/A
