PolysacDB Glucosyl ceramide 1895
From DrugPedia: A Wikipedia for Drug discovery
[edit] Carbohydrate Name
Glucosyl ceramide
[edit] Carbohydrate Class
Miscellaneous
[edit] Source Microbe
Paracoccidiodes brasiliensis
[edit] Basic Structure
N/A
[edit] Proposed functions
N/A
[edit] Antigenic Nature used to produce antibodies
Whole cells
[edit] Carrier Name
nil
[edit] Conjugation Method
nil
[edit] Antibodies
Mab MEST2
[edit] Antibody type and class
IgG2a
[edit] Assay System
High performance thin layer chromatography immunostaining, solid phase radioimmunoassay
[edit] Cross-reactivity
This Mab cross-reacts with glucosyl ceramide from Histoplasma capsulatum, Sporothrix schenckii, Aspergillus fumigatus, Candida albicans, Cryptococcus neoformans, Cryptococcus laurentii and Cryptococcus albidus
[edit] Proposed epitopes
β-D-glucose residues and 2-hydroxyl groups in the fatty acid groups seemed to a important part of the epitoipe
[edit] Proposed Utility
This Mab should act as an effective reagent in studies for the distribution of glycoinositol-phosphoryl ceramides in the plasma membrane of different fungi
